{"product_id":"calsequestrin-2-dog-casq2-dog-5ug","title":"Calsequestrin-2 Dog, CASQ2 Dog, 5ug","description":"\u003ctable width=\"100%\" cellspacing=\"0\" cellpadding=\"0\" border=\"0\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan style=\"font-weight: bold; font-family: Calibri; font-size: 10pt; color: rgb(0, 128, 0);\"\u003eCAT No.BT-PRO-410\u003c\/span\u003e\u003c\/td\u003e                                    \u003c\/tr\u003e                                   \u003ctr\u003e                                                \u003ctd\u003e    \u003cspan style=\"font-family: Arial; font-weight: 700; font-size: 12pt; color: rgb(128, 0, 0);\"\u003eCalsequestrin-2 Dog, CASQ2 Dog, 5ug\u003c\/span\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\u003chr\u003e\n\u003cp\u003eApplications\u003cbr\u003eImmunoblots\u003cbr\u003eAbsorption\u003cbr\u003eImmunohistochemistry.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eDescription\u003cbr\u003eCalsequestrin is the major calcium storage protein of the sarcoplasmic reticulum. Intraluminar Ca2+ binds to calsequestrin during diastole to prevent Ca2+ precipitation and to lower its free ionic concentration to facilitate efficient storage. During systole, Calsequestrin coordinately releases ~40?50 Ca2+ ions per molecule for each contraction-relaxation cycle by an uncertain mechanism. Calsequestrin has been shown to be of major importance in the regulation of cardiac excitation-contraction coupling.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eFormulation\u003cbr\u003eThe protein was lyophilized from a concentrated solution (1mg\/ml) containing 10mM Tris-HCl and 1mM EGTA.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003eSterile Filtered White lyophilized (freeze-dried) powder.\u003cp\u003e\u003c\/p\u003e\u003cp\u003ePurity\u003cbr\u003eGreater than 90% as determined by SDS-PAGE.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eSolubility\u003cbr\u003eIt is recommended to reconstitute the lyophilized CASQ2 in sterile 18M?-cm H2O not less than 100ug\/ml, which can then be further diluted to other aqueous solutions.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eSource\u003cbr\u003eDog Heart.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eStability\u003cbr\u003eLyophilized CASQ2 although stable at room temperature for 3 weeks, should be stored desiccated below -18¡ãC. Upon reconstitution CASQ2 should be stored  at 4¡ãC between 2-7 days and for future use below -18¡ãC.\r\nFor long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).\r\nPlease prevent freeze-thaw cycles.\r\n\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eSynonyms\u003cbr\u003eCalsequestrin-2, Calsequestrin cardiac muscle isoform, CASQ2, CSQ.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eUsage\u003cbr\u003eTSZGENE's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":42034466848865,"sku":"BT-PRO-410","price":1756.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0567\/9595\/5297\/files\/recom_protein_p_eeea71b9-6343-42a7-b5e1-e7a9e5f335e3.jpg?v=1741095376","url":"https:\/\/biotangusa.com\/products\/calsequestrin-2-dog-casq2-dog-5ug","provider":"Biotang USA","version":"1.0","type":"link"}