| CAT No.BT-PRO-414 |
| Aprotinin Bovine Recombinant, Aprotinin Bovine, 20mg |
Introduction
Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. Aprotinin is present in blood and in most tissues, with a high concentration in lung. Aprotinin inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins (e.g., CD11b).
Activity
4.6 TIU/mg.
Description
Aprotinin Bovine Recombinant is approximately 6,512 Dalton highly purified and designed specifically for cell culture applications, protein purification, diagnostic testing and pharmaceuticals.
It is produced without the use of animal- or human-derived materials and is therefore free from risk of contaminating human or animal-derived viruses or prions.
The protein was lyophilized without any additives.
Physical Appearance
Sterile Filtered lyophilized powder.
Purity
Greater than 90.0% as determind by Gel Electrophoresis.
Solubility
It is recommended to reconstitute the Aprotinin in sterile 18MO-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Source
Maize (Corn).
Stability
Aprotinin although stable at room temperature for 3 weeks, should be stored at 4¡ãC.
Synonyms
Pancreatic trypsin inhibitor, Basic protease inhibitor, BPI, BPTI, Aprotinin, AP.
Unit Defenition
One Trypsin Inhibitory Unit (TIU) is equal to the amount of inhibitor with the ability to inhibit two trypsin units by 50% where one trypsin unit will hydrolyze 1.0 mmole of N-alpha-benzoyl-DL-Arginine-p-Nitroanilide (BAPNA) per minute at pH 7.8 at 25¡ãC.
Usage
TSZGENE's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
