Ascomycin for Reasearch Use.
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Ascomycin for Reasearch Use.

Supplier: Biotang Inc.
In stock (1000 items available)
  • $99.00
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  • CAT. NO.
    RXL04-50mg
Ascomycin, >95%
Synonyms: Immunomycin;FK-520;FR-520;FR 900520;L 683590

CAS#104987-12-4, M.W.792.01, Formula: C43H69NO12


Cat.# Size Price ($)
RXL04-50mg 50 mg 99
RXL04-200mg 200 mg 319
RXL04-500mg 500 mg 559
RXL04-1g 1g 879
Ascomycin, also called Immunomycin, FR-900520, FK520, is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties.
Ascomycin
acts by binding to immunophilins, especially macrophilin-12. It appears that Ascomycin inhibits the production of Th1 (interferon- and IL-2) and Th2 (IL-4 and IL-10) cytokines. Additionally, ascomycin preferentially inhibits the activation of mast cells, an important cellular component of the atopic response. Ascomycin produces a more selective immunomodulatory effect in that it inhibits the elicitation phase of allergic contact dermatitis but does not impair the primary immune response when administered systemically.
Ascomycin
is produced by the fermentation of Streptomyces hygroscopicus.
  • Manufacturer
    TSZCHEM
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