Microglobulin Alpha-1 Protein Human, A1M Human, 100ug

Human Virus Test
Starting material tested and certified negative for HIV I & II antibodies, Hepatitis B surface antigen, and Hepatitis C antibodies.

03mg/ml) forms a 1
:1 complex with about 5% of plasma immunoglobulin A. The resulting macromolecular complexes¡¯ molecular weight is 200000, and a plasma concentration of 0.3mg/ml. The complex can exhibit both antibody activity and affect many of the biological actions of free Alpha-1-microglobulin.
Alpha-1-microglobulin was first discovered in pathological human urine.
It was suggested that A1M might be involved in tissue defense against reactive oxygen species, oxidation by heme and kynurenin. Evidence also suggests that A1M functions in the regulation of the immune system.

Description
Alpha 1-microglobulin (A1M) is an immunomodulatory protein with a broad spectrum of possible clinical applications and seems a promising marker for evaluation of tubular function.

Other functions include
: inhibition of stimulation of cultured lymphocytes by protein antigens; induction of cell division of lymphocytes, a mitogenic effect that can either be enhanced or inhibited by the action of other plasma components; inhibition of neutrophil granulocyte migration in vitro; and inhibition of chemotaxis.

Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.

Purity
Greater than 96.0%.

Solubility
Use phosphate buffer, pH>7.0 containing 0.15M NaCl, is recommended.

Source
Purified from the urine of patients with chronic renal tubular proteinuria.

Stability
Human A1M although stable at room temperature for 3 weeks, should be stored between 2-8¡ãC.

Synonyms
Alpha-1 Microglobulin, A1M.

Usage
TSZGENE's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.