Important note: Products are intended for laboratory use and are not to be used for any other purpose, which include but are not limited to, unauthorized commercial uses, ex vivo or in vivo therapeutic uses. Not for Human or Animal Consumption.
Recombinant Human Epidermal Growth Factor (EGF), 2 mg
Epidermal growth factor or EGF is a growth factor that plays
an important role in the regulation of cell growth, proliferation, and
differentiation by binding to its receptor EGFR. Human EGF is a 6045-Da protein
with 53 amino acid residues and three intramolecular disulfide bonds.
EGF results in cellular proliferation, differentiation, and
survival.EGF is a low-molecular-weight polypeptide first purified from the
mouse submandibular gland, but since then found in many human tissues including
submandibular gland, parotid gland. Salivary EGF, which seems also regulated by
dietary inorganic iodine, also plays an important physiological role in the
maintenance of oro-esophageal and gastric tissue integrity. The biological
effects of salivary EGF include healing of oral and gastroesophageal ulcers,
inhibition of gastric acid secretion, stimulation of DNA synthesis as well as
mucosal protection from intraluminal injurious factors such as gastric acid,
bile acids, pepsin, and trypsin and to physical, chemical and bacterial agents.
*Lead time 1-2 weeks. Shipped by FedEx.
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