B cell Activating Factor Human Recombinant, His Tag, BAFF Human, His, 20ug

CAT No.BT-CYT-545

B cell Activating Factor Human Recombinant, His Tag, BAFF Human, His, 20ug

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:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" /> IntroductionBinds to tnfrsf13b/taci and tnfrsf17/bcma. tnfsf13/april binds to the same 2 receptors, together, they form a 2 ligands -2 receptors pathway involved in the stimulation of b- and t-cell function and the regulation of humoral immunity. a third b-cell specific baff-receptor (baffr/br3) promotes the survival of mature b-cells and the b-cell response.
B Lymphocyte Stimulator functions as a potent B-cell growth factor in costimulation assays.
Administration of BAFF Human recombinant to mice disrupts splenic B-cell and T-cell zones and results in elevated levels of serum immunoglobulin.

Amino acid sequence
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAV QGPEETVTQDCLQLIADSET PTIQKGSYTF VPWLLSFKRG SALEEKENKI LVKETGYFFI YGQVLYTDKT YAMGHLIQRK KVHVFGDELS LVTLFRCIQN MPETLPNNSC YSAGIAKLEE GDELQLAIPR ENAQISLDGD VTFFGALKLL.

Description
BLyS Human Recombinant fused to His tag at N-terminus produced in E.Coli is a single, non-glycosylated polypeptide chain containing 190 amino acids and having a molecular mass of 21 kDa.
The BAFF His tag fusion protein is purified by proprietary chromatographic techniques.

Recombinant His Tag BAFF contains 20mM Tris buffer pH-8 and 5mM DTT.

Physical Appearance
Sterile Filtered colorless solution.

Purity
Greater than 95.0% as determined by(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Source
Escherichia Coli.

Stability
BLyS although stable at 10¡ãC for 3 weeks, should be stored desiccated below -18¡ãC.
Please prevent freeze-thaw cycles.

Synonyms
BAFF, BLYS, CD257, TALL1, THANK, ZTNF4, TALL-1, TNFSF20, TNFSF13B, B-cell Activating Factor.

Usage
TSZGENE's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.