Granulocyte-Colony Stimulating Factor Pegylated Human Recombinant, G CSF Human, PEG, 10ug

Biological Activity

The ED₅₀, calculated by the dose-dependent proliferation of murine NFS-60 indicator cells is less than 0.1 ng/ml, corresponding to a Specific Activity of 10,000,000IU/mg.

Description
Granulocyte Colony Stimulating Factor Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 175 amino acids and having a molecular mass of 18.8kDa. The Pegylated G-CSF is produced by attaching a 20kDa methoxypolyethylene glycol propionaldehyde (mPEG-ALD) to the N-terminal amino acid of G-CSF giving a total molecular mass of 38.8kDa.
G-CSF is purified by proprietary chromatographic techniques.

Formulation
G-CSF is supplied in solution (0.69mg/ml) containing 10mM Acetate Buffer (pH 4.0), and 0.004% Polysorbate 80.

Colorless, clear and transparent solution.

Purity

Greater than 95.0% as determined by SEC-HPLC.

Source
Escherichia Coli.

Stability

G-CSF PEG should be stored refrigerated at 2¡ã to 8¡ãC. Vials should be kept in theirpackaging to protect from light until the time of use.
Shaking and freezing should be avoided.

Synonyms
CSF-3, MGI-1G, GM-CSF beta, Pluripoietin, Filgrastim, Lenograstim, G-CSF, MGC45931, GCSF.

Usage
TSZGENE's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.