Recombinant Human Bone Morphogenetic protein Receptor-1A HEK, BMPR1A Human HEK, 10ug

CAT No.BT-CYT-713

Recombinant Human Bone Morphogenetic protein Receptor-1A HEK, BMPR1A Human HEK, 10ug

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Amino acid sequence
QNLDSMLHGT GMKSDSDQKK SENGVTLAPE DTLPFLKCYC SGHCPDDAIN NTCITNGHCF AIIEEDDQGE TTLASGCMKY EGSDFQCKDS PKAQLRRTIE CCRTNLCNQY LQPTLPPVVI GPFFDGSIRE NLYFQGGSGT KLDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH GDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGK.

Biological Activity
The biological activity of human BMPR1A is determined by its ability to inhibit human BMP-4 induction of alkaline phosphatase in the mouse chondrogenic cell line ATDC5. The observed ED50 range is from 0.1 to 0.3 ug/ml in the presence of 30ng/ml of recombinant human BMP-4 protein.

Description
BMPR1A Human Recombinant produced in HEK-293 cells is a single, glycosylated, polypeptide chain containing 369 amino acids with a molecular weight of 43.7 kDa though on SDS-PAGE migrates at about 50 kDa due to the glycosilation. The BMPR1A is purified by proprietary chromatographic techniques.

The BMPR1A protein was lyophilized from a 0.2?m filtered solution containing no additives or preservatives.

Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.

Purity
Greater than 95.0% as determined by SDS-PAGE.

Solubility
It is recommended to reconstitute the lyophilized BMPR1A in sterile 18M¦¸-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.

Source
HEK293-F Cells.

Stability
Lyophilized BMPR1A although stable at room temperature for 3 weeks, should be stored desiccated below -18¡ãC. Upon reconstitution BMPR1A should be stored at 4¡ãC between 2-7 days and for future use below -18¡ãC. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Synonyms
BMPR-1A, BMP-R1A, BMPR1A, BMR1A, CD292, CD-292, Serine/threonine-protein kinase receptor R5, SKR5, Activin receptor-like kinase 3, ALK-3, ACVRLK3, EC 2.7.11.30, CD292 antigen.

Usage
TSZGENE's products are furnished for?LABORATORY RESEARCH?USE?ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.