Vascular Endothelial Growth Factor Receptor-2 Fc Chimera Human Recombinant, VEGFR2 Fc Human, 10ug

CAT No.BT-PKA-243

Vascular Endothelial Growth Factor Receptor-2 Fc Chimera Human Recombinant, VEGFR2 Fc Human, 10ug

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Biological Activity
The activity of sVEGFR-2/Fc was determined by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells. The ED50 for this effect is typically 10-30 ng/ml, corresponding to a specific activity of 33,333.33-100,000 units/mg.

Description
Soluble VEGFR-2 Fc Human Recombinant fused with the Fc part of human IgG1 produced in baculovirus is a disulfide-linked homodimeric, glycosylated, polypeptide containing 757 amino acids and having a molecular mass of 160 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding.
The sKDR Fc Chimera is purified by proprietary chromatographic techniques.

Formulation
KDR fusion protein was lyophilized from a concentrated (1 mg/ml) sterile solution containing 1x PBS pH-7.2.

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity
Greater than 90.0% as determined by SDS-PAGE.

Solubility
It is recommended to reconstitute the lyophilized VEGFR2 in sterile water not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Source
Insect Cells.

Stability
Lyophilized VEGFR-2 Fc/Chimera protein although stable at room temperature for 3 weeks, should be stored desiccated below -18¡ãC. Upon reconstitution FLK1 should be stored at 4¡ãC between 2-7 days and for future use below -18¡ãC.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Synonyms
KDR D1-7, sKDR D1-7, Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1, CD309, type III receptor tyrosine kinase, FLK1, VEGFR-2.

Usage
TSZGENE's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.