| CAT No.BT-PKA-232 |
| Fibroblast Growth Factor Receptor 3 Fc Chimera Human Recombinant, FGFR3 Human, 10ug |
Biological Activity
Determined by its ability to inhibit human FGF acidic-dependent proliferation on R1 cells. The ED50 for this effect is typically at 15.0-30.0 ng/ml.
Description
Soluble FGFR-3a (IIIc) Fc Chimera Human Recombinant fused with Xa cleavage site with the Fc part of human IgG1 produced in baculovirus is a heterodimeric, glycosylated, Polypeptide chain and having a molecular mass of 190 kDa.
The FGFR3 is purified by proprietary chromatographic techniques.
Formulation
CD333 was lyophilized from a concentrated (1 mg/ml) sterile solution containing no additives.
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity
Greater than 90.0% as determined by(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Solubility
It is recommended to reconstitute the lyophilized FGFR-3 in sterile PBS not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Source
Insect Cells.
Stability
Lyophilized FGFR3A although stable at room temperature for 3 weeks, should be stored desiccated below -18¡ãC. Upon reconstitution FGFR3 should be stored at 4¡ãC between 2-7 days and for future use below
-18¡ãC.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Synonyms
Achondroplasia, Thanatophoric Dwarfism, CD333, ACH, CEK2, JTK4, HSFGFR3EX, FGFR3.
Usage
TSZGENE's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
