| CAT No.BT-PKA-342 |
| Tyrosine Kinase ErbB-3 Human Recombinant, ErbB3 Human, 20ug |
Amino Acid Sequence
MRANDALQVL GLLFSLARGS EVGNSQAVCP GTLNGLSVTG DAENQYQTLY KLYERCEVVM GNLEIVLTGH NADLSFLQWI REVTGYVLVA MNEFSTLPLP NLRVVRGTQV YDGKFAIFVM LNYNTNSSHA LRQLRLTQLT EILSGGVYIE KNDKLCHMDT IDWRDIVRDR DAEIVVKDNG RSCPPCHEVC.
Biological Activity
Measured by its ability to postpone tumor emerge time of spontaneous breast cancer in FVB/N transgenic mice and inhibit the development of tumor, effectively inhibit the growth of in situ transplanted breast cancer in FVB/N transgenic mice.
Description
Tyrosine Kinase ErbB3 Human Recombinant (extracellular domain) (HER3) produced in E.Coli is a single, non-glycosylated, fusion polypeptide chain containing Thyrodoxin Tag and His tag. The protein consists of 190 amino acids (Met1- Cys190) and having a total molecular mass of 34 kDa.
The ErbB3 is purified by proprietary chromatographic techniques.
Each mg protein contains 1 mg aluminum hydroxide 10mM arginine, 10mM sodium chloride, 20mM sodium phosphate buffer and 5mM potassium phosphate.
Physical Appearance
A white semitransparent suspension at a concentration of 1 mg/ml.
Purity
Greater than 95.0% as determined by(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Source
Escherichia Coli.
Stability
ErbB3 although stable at 4¡ãC for 1 week, should be stored desiccated below -18¡ãC.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Synonyms
Receptor tyrosine-protein kinase erbB-3, EC 2.7.10.1, c-erbB3, Tyrosine kinase-type cell surface receptor HER3, ErbB3, HER3.
Usage
TSZGENE's products are furnished forLABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
